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Leif E. Peterson, PhD, Principal

Dr. Peterson is Principal of NXG Logic, LLC which develops scientific software for machine learning, neural networks, statistical analysis, and text mining.  He has developed numerous algorithms for data analysis involving text mining, non-linear manifold learning, matrix algebra, eigendecomposition, optimization, and Monte Carlo simulation.  He has published more than 100 peer-reviewed scientific journal articles, US Gov't technical reports and monographs, and the books FORD - A Screenplay,  Effects of Ionizing Radiation: Atomic Bomb Survivors and Their Children (National Academies Press), and Classification Analysis of DNA Microarrays (Wiley).  He is a Senior Member of the Institute for Electrical and Electronics Engineers (IEEE), and a member of its Computational Intelligence Society (CIS).  He served on the IEEE-CIS Bioinformatics and Bioengineering Technical Committee (BBTC), and the IEEE-CIS-BBTC Task Force on Neural Networks. He participates in numerous international machine learning and computational intelligence conferences as listed below.

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Online PhD Dissertation  - US Dept. of Energy, Office of Scientific and Technical Information.   Research Organization: US Nuclear Regulatory Commission, Washington, DC (United States). Div. of Regulatory Applications.


Research Interests

Mathematical algorithms, computational methods, including linear algebra, eigendecomposition, text mining, machine learning, network science, and numerical optimization.


Education

B.S. - Ferris State Univ. (Nuclear Medicine)
M.P.H. - Univ. of Michigan (Radiological Physics)
Ph.D.  - Univ. of Texas (Epidemiology-Biostatistics)


Employment

1984-1986 Adult General Hospital, University of Michigan
1986-1995 Kelsey-Seybold Clinic, NASA/JSC, National Aeronautics and Space Administration
1995-2006 Baylor College of Medicine
2006-2019 Houston Methodist Research Institute (Cornell Univ. faculty appointments)
2019-Pres NXG Logic LLC
2022-Pres Rice University


Positions

1981-1981 Undergraduate Intern, Diagnostic Imaging and Nuclear Medicine, Sinai Hospital of Detroit
1984-1986 Assistant Physicist, Medical Nuclear Physics, Adult General Hospital, University of Michigan
1985-1985 Graduate Intern, Radiation Physics, Sinai Hospital of Detroit
1986-1995 Shuttle Mission Radiation Specialist, Kelsey-Seybold Clinic, National Aeronautics and Space Administration
1995-2004 Assistant Professor, Department of Medicine, Baylor College of Medicine (primary appt)
1997-2005 Consultant, Science Advisory Board, Office of the Administrator, Environmental Protection Agency
1999-2004 Expert Consultant, Space Radiation Health Initiative, National Aeronautics and Space Administration
2000-2006 Assistant Professor, Dept. Molec. and Human Genetics, Baylor College of Medicine (2nd appt)
2002-2003 Visiting Scientist, Lawrence Livermore National Laboratory
2004-2006 Associate Professor, Department of Medicine, Baylor College of Medicine
2004-2006 Associate Professor, Dept. Molec. and Human Genetics, Baylor College of Medicine (2nd appt)
2006-2019 Biostatistician, Center for Biostatistics, Houston Methodist Research Institute
2007-2019 Adjunct Associate Professor, Dept. of Medicine, Baylor College of Medicine
2009-2019 Associate Professor of Public Health, Weill Cornell Medical College, Cornell University
2011-2019 Adjunct Associate Professor of Biostatistics, Division of Biostatistics, University of Texas, School of Public Health
2013-2019 Adjunct Associate Professor, Department of Neuroscience & Experimental Therapeutics. TAMU
2014-2019 Associate Prof of Biostatistics, Institute of Academic Medicine, Houston Methodist Research Institute
2016-2019 Professor of Bioinformatics and Biostatistics, Institute for Academic Medicine, Houston Methodist Research Institute
2017-2019 Professor of Healthcare Policy and Research, Dept. of Healthcare Policy and Research, Weill Cornell Medical College, Cornell University
2019-Pres Principal, NXG Logic, LLC
2022-Pres Lecturer, Department of Statistics, Rice University


NIH Study Sections (Grant Review Panels)

DOE - Integrated Biological and Computational Low Dose Radiation Research, Office of Science, Biological and Environmental Research (BER), 2024
NIAID - Investigator Initiated Program Project Applications (P01): ZAI1-KJK-I-S2, 2020
NIAID - Nonhuman Primate (NHP) Radiation Survivor Cohort (RSC), Special Emphasis Panel: ZAI1-KJK-I-J1, 2019
NIAID Centers for Radiation/Nuclear Predictive Biomarkers and Biodosimetric Devices(U19), ZAI1-LAR-I-C1(Sep), 2017
NIAID Centers for Medical Countermeasures against Radiation Consortium (U19), ZAI-1 PA-I-M2(Mar), 2015
NIAID Centers for Excellence in Translational Research (U19), ZAI1-LR-M-J1(May), 2013
DOD Prostate Cancer Research Program (Jun) - Molecular Biology & Genetics, 2008
DOD Breast Cancer Research Program (Jun) - Molecular Biology & Genetics, 2007
DOD Prostate Cancer Research Program (Jun) - Molecular Biology & Genetics, 2007
DOD Prostate Cancer Research Program (Jun) - Molecular Biology & Genetics, 2006
NCI Special Emphasis Panel-Early Detection Research Network, Cancer Proteomics (Mar), 2005
DOD Breast Cancer Research Program (Jun) - Molecular Biology & Genetics, 2005
NCI Special Emphasis Panel-Contracts for Russian Radioepidemiological Studies(Jun), 2004
NCI Special Emphasis Panel-Early Detection Research Network,Cancer Proteomics (Jul), 2004
NIH ZRG 1 SNEM-2(Mar) S. (Behavioral Genetics), 2003
NIAMS Microarray Review (Aug), 2003
NIH ZRG 1 SNEM-2(Feb) S. (Behavioral Genetics), 2002
NIH ZRG 1 SNEM-2(Jul) S. (Behavioral Genetics), 2002
NCI SPORE Review Panel (Oct), 2002
NIH ZRG 1 SNEM-2(Oct) S. (Behavioral Genetics), 2001
NIH ZRG 1 RAD(04) Radiation, 2001


Teaching

Undergraduate
2024 STAT-305: Spring - Introduction to Statistics for Biosciences, Department of Statistics, Rice University
2024 STAT-280: Spring - Elementary Applied Statistics, Department of Statistics, Rice University
2023 STAT-305: Fall - Introduction to Statistics for Biosciences, Department of Statistics, Rice University
2023 STAT-280: Fall - Elementary Applied Statistics, Department of Statistics, Rice University
2023 STAT-385: Spring - Methods for Data Analysis and System Optimization, Department of Statistics, Rice University
2023 STAT-305: Spring - Introduction to Statistics for Biosciences, Department of Statistics, Rice University
2023 STAT-280: Spring - Elementary Applied Statistics, Department of Statistics, Rice University
2022 STAT-305: Fall - Introduction to Statistics for Biosciences, Department of Statistics, Rice University
2022 STAT-280: Fall - Elementary Applied Statistics, Department of Statistics, Rice University
2022 STAT-305: Fall - Introduction to Statistics for Biosciences, Department of Statistics, Rice University
2008 5310: Fundamentals of Biostatistics & Data Management (Primary Instructor) College of Technology, Univ. of Houston
2007 Primer of Statistics for Computer Science Students (Invited speaker) Dept. of Computer Science, Univ. of Houston
2007 Machine Learning and Computational Intelligence (Invited speaker) Department of Computer Science, Univ. of Houston
2004 Research Methods Course (Instructor), Allied Health Program, 15 hours, Block 4 Dept. of Medicine, Baylor College of Medicine

Graduate
2016 PH-9997: Practicum in Biostatistics (Student: Zhe Dong), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2015 PH-1690: Foundations of Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2015 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2015 PH-9997: Practicum in Biostatistics (Student: Maxine Olefsky), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2015 PH-1997: Individual Study in Biostatistics (Student: Ming Yang), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2015 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2014 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2014 PH-1998: Data Mining Methodology (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2013 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2013 PH-1690: Foundations of Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2013 PH-1998: Data Mining Methodology (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2013 PH-1690: Foundations of Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2012 PH-1690: Foundations of Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2012 PH-1690: Foundations of Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2012 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2011 PH-1700: Intermediate Biostatistics (Primary Instructor), Department of Biostatistics, School of Public Health, University of Texas, Health Science Center at Houston
2001-2002 Quantitative Genetics (Primary Instructor), Graduate School of Biomedical Sciences, 15 hours, Block 4, Dept. of Molecular & Human Genetics Medicine, Baylor College of Medicine


Mentoring

2016-2020 Doctoral Candidacy Committee, Kristine Ferrone, Medical Physics Dept., University of Texas, Graduate School of Biomedical Sciences, U.T.-M.D. Anderson Cancer Center.
2018 Dissertation Reviewer, Marco Notaro, Dept. of Computer Science, University of Milan, Italy.  ``Hierarchical Ensemble Methods for Ontology-based Predictions in Computational Biology.''
2015 Practicum in Biostatistics, Maxine Olefsky, M.S. Student in Biostatistics, Dept. of Biostatistics, University of Texas, School of Public Health
2013-2016 Doctoral Candidacy Committee, Texas A & M University M.D./Ph.D. Program, Ricky Savjani, ``Decoding Visual and Sensory Processing via Human functional MRI and Human Deep Brain Recordings.'' Dept. of Neuroscience, Baylor College of Medicine
2013-2014 Master Thesis Committee, Univ. of Texas, School of Public Health, Tatiana Kovyrshina ``Molecular Pathway Activation in Cancer and Tissue Following Space Radiation Exposure.''
2013-2014 Master Thesis Committee, Univ. of Texas, School of Public Health, Joseph Lubega, M.D. ``Trends of Childhood Acute Lymphocytic Leukemia and Population Mixing in the State of Texas''
2013-2014 PhD/DSc Committee for Computer Science, Machine Intelligence Unit, Indian Statistical Institute, Kolkata. (Ph.D. Student: Ranajit Das) ``Some Issues in Gene Regulation and Evaluation''). Supervisor: Prof. Sushmita Mitra, MIU, ISI Kolkata.
2013 Yeming (Alex) Ge, B.A., Columbia University, The Methodist Hospital Research Institute summer student, Applied Mathematics.
2011-2012 Vittorio Fortino, M.S., Doctoral student in Systems Biology at University of Salerno, IT and Visiting Research Fellow at TMHRI.
2011 Dillon Nguyen, B.S. University of Houston, The Methodist Hospital Research Institute summer student, Pre-Med.
2011 Liang Gu, B.S. Northwestern University, The Methodist Hospital Research Institute summer student, Pre-Med.
2009 Shaun Khan, B.E. University of Houston, The Methodist Hospital Research Institute summer student, Bioengineering.
2007-2009 Doctoral Candidacy Committee, Graduate School of Biomedical Sciences, Baylor College of Medicine (Ph.D. Student: Vijay Nambi, M.D., Ballantyne Lab, Dept. of Medicine).
2007-2009 Madhuri Vasudevan, M.D., M.P.H., ``The Effect of Diet-Induced Weight Loss on HDL Functionality: Investigating Changes in Reverse Cholesterol Transport.'' Clinical Endocrinology and Atherosclerosis Fellow, Center for Cardiovascular Disease Prevention, Dept. of Medicine, Baylor College of Medicine.
2005-2008 Doctoral Candidacy Committee, Graduate School of Biomedical Sciences, Baylor College of Medicine (Ph.D. Student: Victor D. Acevedo, Spencer Lab, Dept. of Immunology).
2005-2007 Doctoral Candidacy Committee, Graduate School of Biomedical Sciences, Baylor College of Medicine (Ph.D. Student: Daniel Amador, Darlington Lab, Dept. of Medicine).
2004-2005 Doctoral Candidacy Committee, Graduate School of Biomedical Sciences, Baylor College of Medicine (Ph.D. Student: Divy Khurana, Cai Lab, Dept. of Molec. and Human Genetics).
2004 Master's Thesis Committee, Graduate School of Biomedical Sciences, Baylor College of Medicine (M.S. Student: Christine Millare).
2003 Herb Singh, M.D., ``Gene expression profiling of prostate cancer and stromal invasion.'' Scott Dept. of Urology Fellow, Baylor College of Medicine.
2001 Doctoral Candidacy Committee, Graduate School of Biomedical Sciences, University of Texas - Health Science Center at Houston (Dr. Hui Xu, John Clifford Lab, UTMDACC).
2000 Master's Thesis Committee, UT School of Public Health, University of Texas - Health Science Center at Houston (Dr. Irina Volguina).
2000-2001 IAEA Fellowship (Dr. Zhanat Abylkassimova, Semipalatinsk, Kazakhstan). International Atomic Energy Agency, Dept. of Medicine, Baylor College of Medicine


Institutional Committees

1990-1995 Medical Isotopes Operations Subcommittee of the Lyndon B. Johnson Space Center Radiation Safety Committee, National Aeronautics and Space Administration, Houston, TX
1992-1995 Astronaut Radiation Constraints Panel, Lyndon B. Johnson Space Center, National Aeronautics and Space Administration, Houston, Texas        
1992-1995 Radiation Safety Committee, Lyndon B. Johnson Space Center, National Aeronautics and Space Administration, Houston, TX        
1993-1995 Human Research Policy and Procedures Committee, Lyndon B. Johnson Space Center, National Aeronautics and Space Administration, Houston, TX        
1995-1996 Organizing Committee of the First Annual Schull International Symposium William J. Schull Institute, Houston, TX        
1997-1998 Uncertainty in Radiogenic Risks Subcommittee (URRS), U.S. Environmental Protection Agency, Washington, DC        
2000-2011 Organizing Committee, NASA Space Radiation Modeling Workshop National Aeronautics and Space Administration, Houston, TX        
2000-2006 Institutional Review Board(3), Baylor College of Medicine, Houston, TX
2000-2001 Patent and Copyright Committee, Baylor College of Medicine, Houston, TX
2003-2004 Prostate Cancer Gene Therapy Working Group, Baylor College of Medicine, Houston, TX
2004-2005 Prostate Cancer Screening Working Group, Baylor College of Medicine, Houston, TX
2006-2019 Institutional Review Board, Houston Methodist Research Institute, Houston, TX
2010-2012 NASA Lung Cancer Consortium External Advisory Committee        
2014-2017 Biostatistics Student Selection/Exemption Committee - UTSPH
2014-2018 Advisory Panel, Radiation and Public Health Project        


International Conference and Society Leadership

Conference Chair - First Industrial Conference on Artificial Intelligence and Health (ICAIH19)        
Session Chair - Fast and Efficient Solutions for Computational Intelligence Methods in Bioinformatics, Systems and Computational Biology, Fifteenth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB18)         
General Chair - Fourteenth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB17)        
Session Chair - Machine Learning for Enhancing Biomedical Data Analysis, 2017 International Joint Conference on Artificial Neural Networks (IJCNN 17)        
Session Chair - Computational Biostatistics for Data Integration in Systems Biomedicine, Eleventh International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB14)        
General Chair - Ninth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB12)        
Session Chair - Intelligent Clinical Decision Support Systems (i-CDSS), Seventh International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB11)        
Session Chair - Machine Learning and Computational Intelligence in Biomedicine (MLCIB10) - The Eighth Annual IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB11)        
Track Chair - Computational Intelligence for Biopattern Data Analysis, 2010 International Joint Conference on Neural Networks (IJCNN10)        
Session Chair - Computational Intelligence for Biopattern Data Analysis, 2010 International Joint Conference on Neural Networks (IJCNN10)
Session Chair - Computational Intelligence for Biopattern Data Analysis: Bioinformatics I, 2010 International Joint Conference on Neural Networks (IJCNN10)        
Session Chair - Computational Intelligence for Biopattern Data Analysis: Bioinformatics II, 2010 International Joint Conference on Neural Networks (IJCNN10)        
Session Chair - Computational Intelligence for Biopattern Data Analysis: Bioinformatics III, 2010 International Joint Conference on Neural Networks (IJCNN10)        
Session Chair - Intelligent Clinical Decision Support Systems (i-CDSS), Seventh International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB10)        
General Chair - Sixth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB09)        
Session Chair - Diagnosis, Prognosis, and Survival Analysis with Biopatterns using Machine Learning Methods - Eighth International Conference on Machine Learning and Applications (ICMLA 2009)        
Session Chair - From Desktop to Bedside - Computational Intelligence for Biopattern, 2009 International Joint Conference on Neural Networks (IJCNN09)        
Chair - Houston-Area Chapter, IEEE Computational Intelligence Society, 2008
Session Chair - Application of Machine Learning in Constructing Biopatterns and Analyzing Bioprofiles - Seventh International Conference on Machine Learning and Applications (ICMLA08)        
Area Chair - Bioinformatics and Medical Applications - 7th Mexican International Conference on Artificial Intelligence (MICAI08)        
Session Chair - Analysis of High Dimensional Data in Bioinformatics, 2008 International Joint Conference on Neural Networks (IJCNN08)        
Co-Chair - Workshop on Machine Learning in Biomedicine and Bioinformatics (MLBB07) of the Sixth International Conference on Machine Learning and Applications (ICMLA07)        
Session Chair - Neural Network Applications in Bioinformatics, 2007 International Joint Conference on Neural Networks (IJCNN07)        
Vice Chair - Houston-Area Chapter, IEEE Computational Intelligence Society, 2007        
Chair - Houston-Area Chapter, IEEE Computational Intelligence Society, 2006


International Conference Steering/Program Committees        

Technical Program Committee - 2022 World Congress on Computational Intelligence (WCCI22)
Technical Program Committee - 2021 International Joint Conference on Neural Networks (IJCNN21)
Technical Program Committee - 2020 International Joint Conference on Neural Networks (IJCNN20)
Steering Committee - 15th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB19)        
Steering Committee - 15th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB18)        
Program Committee - 2017 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB2017)        
Steering Committee - 14th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB17)        
Steering Committee - International Conference on Big Data Analytics and Computational Intelligence(ICBDACI2017)        
Steering Committee - 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB16)        
International Program Committee - 18th International Conference on Enterprise Information Systems (ICEIS2015)        
Steering Committee - 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB15)        
International Program Committee - 2015 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB 2015)        
International Program Committee - International Joint Conference on Neural Networks (IJCNN15)        
International Program Committee - 17th International Conference on Enterprise Information Systems (ICEIS 2015)        
Steering Committee - 1st International Conference on Contemporary Computing and Informatics (ICI3I14)        
Steering Committee - 11th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB14)        
International Scientific Committee - Genoa Bioinformatics Workshop, Interacting proteins: a computational intelligence challenge, 2013-06-14, Sala conferenze DIBRIS-Valletta Puggia, Via Dodecaneso, 35 Genova, Italy,2013
International Program Committee - The Second International Conference on Intelligent Systems and Applications INTELLI13        
Steering Committee - 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB13)        
International Program Committee - 14th International Conference on Enterprise Information Systems (ICEIS12)        
Scientific Committee - 8th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB11)        
International Program Committee - Healthcare Informatics, Imaging, and Systems Biology (HISB11)        
Technical Program Committee - The Third International Conferences on Pervasive Patterns and Applications (PATTERNS 2011)        
International Program Committee - 4th International Conference on Pattern Recognition and Machine Intelligence (PReMI11)        
International Program Committee - 12th International Conference on Enterprise Information Systems (ICEIS11)        
Scientific Committee - 7th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB10)        
International Program Committee - 3rd International Conference on Agents and Artificial Intelligence (ICAART10)        
International Program Committee - 12th International Conference on Enterprise Information Systems (ICEIS2010)        
Member, Technical Committee on Machine Learning, IEEE Systems, Man, and Cybernetics Society (2009)        
Member, Technical Committee on Computational Intelligence, IEEE Systems, Man, and Cybernetics Society (2009)        
International Program Committee - Bioinformatics and Medical Applications track, 8th Mexican International Conference on Artificial Intelligence (MICAI 2009)        
International Program Committee - Intelligent Systems for Medical Decision Support (ISMDS 2009)        
International Program Committee - International Conference on Soft Computing and Pattern Recognition (SoCPaR 2009)        
International Program Committee - World Congress on Nature and Biologically Inspired Computing (NaBIC 2009)        
International Program Committee - International Conference on Agents and Artificial Intelligence (ICAART 2009)        
International Program Committee - International Conference on Bio-inspired Systems and Signal Processing (BIOSIGNALS 2009)        
International Program Committee - International Conference on Health Informatics (HEALTHINF 2009)        
International Program Committee - Workshop on Supervised and Unsupervised Ensemble Methods and Their Applications (SUEMA 2008), of the European Conference on Artificial Intelligence (ECAI 2008)        
International Program Committee - 11th International Conference on Enterprise Information Systems(ICEIS 2009) International Program Committee - Intelligent Systems for Medical Decisions Support (ISMDS 2008)        
International Program Committee - Fifth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB08)        
Organizing Committee - 7th International Conference on Machine Learning and Applications (ICMLA08)        
International Program Committee - 2008 IEEE World Congress on Computational Intelligence (WCCI 2008)        
International Program Committee - 10th International Conference on Enterprise Information Systems(ICEIS 2008)        
International Program Committee - International Conference on Bio-inspired Systems and Signal Processing (BIOSIGNALS 2008)        
International Program Committee - International Conference on Health Informatics (HEALTHINF 2008)        
International Program Committee - 6th International Conference on Machine Learning and Applications (ICMLA07)        
International Program Committee - Post-IJCNN Workshop on Computational Intelligence Approaches for the Analysis of Bioinformatics Data (CIBIO07)        
International Program Committee - Fourth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB07)        
International Program Committee - Bioinformatics, Machine Learning, Statistics - EUROCON 2007 IEEE International Conference on Computer as Tool (EUROCON07)
International Program Committee - First IEEE Symposium on Foundations of Computational Intelligence (FOCI07)
International Program Committee - 2007 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB07)        
International Program Committee - 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB06)        
International Program Committee - Third International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB06)        
International Program Committee - 2006 IEEE World Congress on Computational Intelligence(WCCI06)-International Joint Conference on Neural Networks (IJCNN06)        


Peer-Reviewed Publications

Peterson, L.E. Optimization of classifier ensemble diversity. Academia Molecular Biology and Genomics 2024;1.
https://doi.org/10.20935/AcadMolBioGen7288

Peterson, L.E.  Improved Dimension Reduction for Pattern Classification Using Noise Eigenspace Projection. International Journal of Data Science and Big Data Analytics, 4(1), 34-51. https://doi.org/10.51483/IJDSBDA.4.1.2024.34-51

Ferrone, K.L., Willis, C.E., Guan, F., Ma, J., Peterson, L.E., Kry, S.F. Evaluating bone marrow dosimetry with the addition of bone marrow structures to the MIRD phantom.   Precision Radiation Oncology.  2023: 1-9.  DOI: 10.1002/pro6.1189.

Ferrone, K.L., Willis, C.E., Guan, F., Ma, J., Peterson, L.E., Kry, S.F.  A review of magnetic shielding technology for space radiation.  Radiation.   3: 46-57; 2023.  DOI: 10.3390/radiation3010005.

Peterson, L.E.  Covid-19 and Flavonoids: In silico Molecular Dynamics Docking to the Active Catalytic Site of SARS-CoV and SARS-CoV-2 Main Protease.    Afr. J. Pharmaceutical Sciences.  2(1):23-42; 2022.

Peterson, L.E.  In Silico Molecular Dynamics Docking of Drugs to the Inhibitory Active Site of SARS-CoV-2 Protease and Their Predicted Toxicology and ADME.   Afr. J. Pharmaceutical Sciences.  1(1): 16-39; 2021. 

Cathcart, S.J., Appel, S.H., Peterson, L.E., Greene, E.P., Powell, S.Z., Arumanayagam, A.S., Rivera, A.L., and Cykowski, M.D. 2021. Fast progression in amyotrophic lateral sclerosis is associated with greater TDP-43 burden in spinal cord. J Neuropathol Exp Neurol.  80(8): 754-763; 2021.

Regnier-Golanov, A.S., Dündar, F., Zumbo, P., Betel, D., Hernandez, M.S., Peterson, L.E., Lo, E.H., Golanov, E.V., Britz, G.  Hippocampal Transcriptome Changes after Subarachnoid Hemorrhage in Mice.  Frontiers in Neurology.  12: 1134; 2021.

Ferrone, K.L., Guan, F., Ma, J., Peterson, L.E., Willis, C.E., Kry, S.F.   Reducing space radiation cancer risk with magnetic shielding.  Advances in Space Research.  68(1): 153-160; 2021.

Lador, A., Peterson, L.E., Swarup, V., Schurmann, P.A., Makkar, A., Doshi, R.N., DeLurgio, D., Athill, C.A., Ellenbogen, K.A., Natale, A., Koneru, J., Dave, A.S., Giorgberidze, I., Afshar, H., Guthrie, M.L., Bunge, R., Morillo, C.A., Kleiman, N.S., Valderrábano, M.  Determinants of outcome impact of Vein of Marshall Ethanol infusion when added to catheter ablation of persistent atrial fibrillation: A secondary analysis of the VENUS randomized clinical trial.   Heart Rhythm. 18(7):1045-1054; 2021.

Valderrábano, M., Peterson, L.E., Swarup, V., Schurmann, P.A., Makkar, A., Doshi, R.N., DeLurgio, D., Athill, C.A., Ellenbogen, K.A., Natale, A., Koneru, J., Dave, A.S., Giorgberidze, I., Afshar, H., Guthrie, M.L., Bunge, R., Morillo, C.A., Kleiman, N.S.   Effect of Catheter Ablation With Vein of Marshall Ethanol Infusion vs Catheter Ablation Alone on Persistent Atrial Fibrillation - The VENUS Randomized Clinical Trial.   JAMA. 324(16):1620-1628; 2020.

Vera, A.M., Barrera, B.D., Peterson, L.E., Yetter, T.R., Dong, D., Delgado, D.A., McCulloch, P.C., Varner, K.E., Harris, J. D.    An Injury Prevention Program for Professional Ballet: A Randomized Controlled Investigation.  Orthopaedic Journal of Sports Medicine.  8(7): 1-12; 2020.

Lubega, J., Hallman, M.D., Lupo, P.J., Fu, Y., Peterson L.E., Scheurer, M.E. Association of population mixing and acute lymphocytic leukemia in children and young adults. Cancer Epidemiol.  66:101722; 2020.

Vera, A.M., Peterson, L.E., Dong,D., Haghshenas, V.,  Yetter, T.R., Delgado, D.A., McCulloch, P.C., Varner, K.E., Harris, J.D. High Prevalence of Connective Tissue Gene Variants in Professional Ballet.  Am. J. Sports Med.  48(1): 222-228; 2019.

Peterson, L.E., Kovyrshina, T.  DNA Repair Gene Expression Adjusted by the PCNA Metagene Predicts Survival in Multiple Cancers.  Cancers. 11(4), 501; 2019.

Sochacki, K.R., Dong, D., Peterson, L.E., McCulloch, P.C., Lisman, K., Harris, J.D.  Overnight call is associated with poor resting heart rate and heart rate variability in orthopaedic surgeons.    Journal of ISAKOS: Joint Disorders & Orthopaedic Sports Medicine.   4: 123-126; 2019.. 

Peterson L.E. Small Molecule Docking of DNA Repair Proteins Associated with Cancer Survival Following PCNA Metagene Adjustment: A Potential Novel Class of Repair Inhibitors. Molecules. 24(3):645-666; 2019.

Valderrábano, M., Peterson, L.E., Bunge R, Prystash, M., Dave, A.S., Nagueh, S.,  Kleiman, N.S. Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design. Am Heart J.  215:52-61; 2019.

Sochacki, K.R., Dong, D., Peterson, L.E., McCulloch, P.C., Harris, J.D. The Measurement of Orthopaedic Surgeon Quality and Quantity of Sleep Using a Validated Wearable Device. J Am Acad Orthop Surg Glob Res Rev. 2(10): e065; 2018.

Rehman, H., Reardon, M., Kleiman, N., Peterson, L.E., Kalra, A.   Balloon Predilation in Transcatheter Aortic Valve Replacement with Self-Expanding Valves.  Structural Heart: The Journal of The Heart Team.  2018 Dec 17.  [Epub ahead of print].

Zhang, M., Suarez, E., Vasquez, J.L., Nathanson, L., Peterson, L.E., Rajapakshe, K., Basil, P., Weigel, N.L., Coarfa, C., Agoulnik, I.U.  Inositol polyphosphate 4-phosphatase type II regulation of androgen receptor activity. Oncogene. 2018 Sep 18. [Epub ahead of print].

Phillips, R.A., Xu, J., Peterson, L.E., Arnold R.M., Diamond, J.A., Schussheim, A.E. Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension.  J. Am. Coll. Cardiol. 71(15): 1601-1610; 2018.

Peterson, L.E., Kovyrshina, T.  Progression Inference for Somatic Mutations in Cancer.  Heliyon. 33: e00277; 2017.

Cykowski, M.D., Powell, S.Z., Peterson, L.E., Appel, J.W., Rivera, A., Takei, H., Chang, E., and Appel, S.H. Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis. J. Neuropathol. Exp. Neurol. 76(5): 402-413; 2017.

Edmondson, D.A., Karski, E.E., Kohlgruber, A., Koneru, H., Matthay, K.K., Allen, M., Hartman, C.L., Peterson, L.E., DuBois, S.G., Coleman, M.A.  Transcript analysis for internal biodosimetry using peripheral blood from neuroblastoma patients treated with (131)I-mIBG, a targeted radionuclide.  Radiation Research. 186(3): 235-244; 2016.

Sridharan, D., Asaithamby, A., Blattnig, S., Costes, S., Doetsch, P., Dynan, W., Hahnfeldt, P., Hlatky, L., Kidane, Y., Kronenberg, A., Naidu, M., Peterson, L.E., Plante, I., Ponomarev, A., Saha. J., Snijders, A., Werner, E., Pluth, J.M. Evaluating Biomarkers to Model Cancer Risk Post Cosmic Ray Exposure. Life Sciences in Space Research.  9:19-47; 2016.

Whiddon, A.R., Dawson, K.L., Fuentes, A., Perez, K.K., Peterson, L.E., Kaleekal, T. Post-operative antimicrobials after lung transplantation and the development of multidrug resistant bacterial and Clostridium difficile infection: an analysis of 500 non-cystic fibrosis lung transplant patients. Clin Transplant. 30(7):767-773; 2016.

Lopez, S.M., Agoulnik, A.I., Peterson, L.E., Suarez, E., Gandarillas, G.A., Frolov, A., Li, R., Rajapakshe, K., Coarfa, C., Ittmann, M.M., Weigel, N.L., Agoulnik, I.U. Nuclear Receptor Corepressor 1 expression and output declines with prostate cancer progression, CCR-15-1983R1. Clin. Cancer Res. [E-pub ahead of Print] 29 Feb 2016.

Nabi, F., Kassi, M., Muhyieddeen, K., Chang, S.M., Xu, S., Peterson, L.E., Wray, N.P., Shirkey, B.A., Ashton, C.M., Mahmarian, J.J. Optimizing Evaluation of Patients with Low-to-Intermediate Risk Acute Chest Pain: A Randomized Study Comparing Stress Myocardial Perfusion Tomography Incorporating Stress-only Imaging to Cardiac CT. J. Nucl. Med. 57:378-384; 2016.

Peterson, L.E., Kovyrshina, T. Adjustment of Lifetime Risks of Space Radiation-Induced Cancer by the Healthy Worker Effect and Cancer Misclassification. Heliyon. e00048; 2015.

Salazar, K.L, Zhou, H., Xu, J., Peterson, L.E., Schwartz, M.R., Mody, D.R., Ge, Y. Multiple human papilloma virus infections and impact on the development of high risk cervical lesions. Acta Cytologica. 59(5):391-398; 2015.

Higgins, C.L., Isbilir, S., Basto, P., Chen, I.Y., Vaduganathan, M., Vaduganathan, P., Reardon, M.J., Lawrie, G., Peterson, L.E., Morrisett, J.D. Distribution of alkaline phosphatase, osteopontin, RANK ligand and osteoprotegerin in calcified human carotid atheroma. Protein Journal. 34(5):315-328; 2015.

Coleman, M.A., Sasi, S.P., Onufrak, J., Natarajan, M., Manickam, K., Schwab, J., Muralidharan, S. Peterson, L.E., Alekseyev, Y., Yan, X., Goukassian, D. Low Dose Radiation Affects Cardiac Physiology: Gene Networks and Molecular Signaling in Cardiomyocytes. Heart and Circulatory Physiology. 309(11):H1947-1963; 2015.

Ghebremariam Y.T., Cooke, J.P., Gerhart, W., Griego, C., Brower, J.B., Doyle-Eisele, M., Moeller, B.C., Zhou, Q., Ho, L., de Andrade, J., Raghu, G., Peterson, L.E., Rivera, A., Rosen, G.D. Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis. J Transl Med. 13(1):249; 2015.

Mahmarian, J.J., Peterson, L.E., Xu, J., Cerqueira, M.D., Iskandrian, A.E., Bateman, T.M., Thomas, G.S., Nabi, F. Regadenoson provides perfusion results comparable to adenosine in heterogeneous patient populations: A quantitative analysis from the ADVANCE MPI trials. J Nucl Cardiol. 22(2):248-61; 2015.

Yin, Z., Deng, T., Peterson, L.E., Yu, R., Lin, J., Hamilton, D.J., Reardon, P.R., Sherman, V., Winnier, G.E., Zhan, M., Lyon, C.J., Wong S.T., Hsueh, W.A. Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation. Mol. Cellular Endocrinol. 394(1-2): 80-87; 2014.

Peterson, L.E. Superresolution MUSIC based on Marĉenko-Pastur limit distribution reduces uncertainty and improves DNA gene expression-based microarray classification. LNCS. 8452:191-209; 2014.

Perez, K.K., Olsen, R.J., Musick, W.L., Cernoch, P.L., Davis, J.R., Peterson, L.E., Musser, J.M. Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant gram-negative bacteremia. J. Infect. 69(3):216-225; 2014.

Thomas, A., Peterson, L.E. Reduction of costs for anemia-management drugs associated with the use of ferric citrate. Int. J. Nephrol. Renovasc. Dis. 7:191-201; 2014.

Gupte, A.A., Hamilton, D.J., Cordero-Reyes, A.M., Youker, K.A., Yin, Z., Estep, J.D., Stevens, R.D.,  Wenner, B., Ilkayeva, O., Loebe, M., Peterson, L.E., Lyon, C.J., Wong, S., Newgard, C.B., Torre-Amione, G., Taegtmeyer, H., Hsueh, W.A. Mechanical unloading promotes myocardial energy recovery in human heart failure. Circulation Cardiovascular Genetics. 7(3):266-276; 2014.

Sonpavde, G., Wang, M., Peterson, L.E., Wang, H.Y., Joe, T., Mims, M.P., Kadmon, D., Ittmann, M.M. Wheeler, T.M., Gee, A.P., Wang, R.F., Hayes, T.G. HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer. Investigational New Drugs. 32(2):235-242; 2014.

Peterson, L.E., Ford, C.E. Random matrix theory and covariance matrix filtering for cancer gene expression. LNCS. 7845:173-184; 2013.

Kim, D., Marchetti, F., Chen, Z., Zaric, S., Wilson, R.J., Hall, D.A., Gaster, R.S., Lee, J-R, Wang, J., Osterfeld, S.J., Yu, H., White, R.M., Blakely, W.F., Peterson, L.E., Bhatnagar, S., Manion, B., Tseng, S., Roth, K., Coleman, M.A., Snijders, A.M., Wyrobek, A.J., Wang, S.X. Nanosensor biodosimetry of mouse blood proteins after exposure to ionizing radiation. Scientific Reports (Nature). 3(2234):1-8; 2013.

Ducharme, N.A., Peterson, L.E., Benfenati, E., Reif, D., McCollum,C.W., Gustafsson, J-A, Bondesson, M. Meta-analysis of toxicity and teratogenicity of 133 chemicals from zebrafish developmental toxicity studies. Reproductive Toxicology. S0890-6238(13):204-209; 2013.

Perez, K.K., Olsen, R.J., Musick, W.L., Cernoch, P.L., Davis, J.R., Land, G.A., Peterson, L.E., Musser, J.M. Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs. Arch. Path. Lab. Med. 137(9):1247-1254; 2013.

Budworth, H., Snijders, A.M., Marchetti, F., Mannion, B., Bhatnagar, S., Kwoh, E., Tan, Y., Wang, S.X., Blakely, W.F., Coleman, M., Peterson, L.E., Wyrobek, A.J. DNA repair and cell cycle biomarkers of radiation exposure and inflammation stress in human blood. PLoS One. 7(11):e48619; 2012.

Xu, J., Lee, E.T., Peterson, L.E., Devereux, R.B., Rhoades, E.R., Umans, J.G., Best, L.G., Howard, W.J., Paranilam, J., Howard, B.V. Differences in risk factors for coronary heart disease among diabetic and nondiabetic individuals from a population with high rates of diabetes: the Strong Heart Study. J. Clin. Endocrinol. Metab. 97(10):3766-3774; 2012.

Chylack, L.T. Jr., Feiveson, A.H., Peterson, L.E., Tung, W.H., Wear, M.L., Marak, L.J., Hardy, D.S., Chappell, L.J., Cucinotta, F.A. NASCA Report 2: Longitudinal study of relationship of exposure to space radiation and risk of lens opacity. Radiat. Res. 178(1):25-32; 2012.

Carroll, R.K., Beres, S.B., Sitkiewicz, I., Peterson, L.E., Matsunami, R.K., Engler, D.A., Flores, A.R., Sumby, P., Musser, J.M. Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus. Epidemics. 3(3-4):159-170; 2011.

Monzon, F.A., Alvarez, K., Peterson, L.E., Truong, L., Amato, R.J., Hernandez-McClain, J., Tannir,  N., Parwani, A.V., Jonasch, E. Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis. Modern Pathol. 24(11):1470-1479; 2011.

Kim, Y.S., Rubio, V., Qi, J., Xia, R., Shi, Z.Z., Peterson, L.E., Tung, C.H., O'Neill, B.E. Cancer treatment using an optically inert Rose Bengal derivative combined with pulsed focused ultrasound. J. Controlled Release. 156(3):315-322; 2011.

Hodgson, M.C., Shao, L-J., Frolov, A., Li, R., Peterson, L.E., Ayala, G., Ittmann, M.M., Weigel, N.L., Agoulnik, I.U. Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer. Cancer Research. 71(2):572-58; 2011.

Grumelli, S., Lu, B., Peterson, L.E., Maeno, T., Gerard, C. CD46 protects against chronic obstructive pulmonary disease. PLoS One. 6(5):e18785; 2011.

Ather, S., Peterson, L.E., Divakaran, V.G., Deswal, A., Ramasubbu, K., Giorgberidze, I., Blaustein, A., Wehrens, X.H.T., Mann, D.L., Bozkurt, B. Digoxin treatment in heart failure - Unveiling risk by cluster analysis of DIG data. Int. J. Cardiol. 150(3):264-269; 2011.

Peterson, L.E. Covariance matrix self-adaptation evolution strategies and other metaheuristic techniques for neural adaptive learning. Soft Computing (Springer). 15(8):1483-1495; 2011.

Alvarez, K., Kash, S.F., Lyons-Weiler, M.A., Kim, H-J., Peterson, L.E., Mathai, B., Hagenkord, J.M., Monzon, F.A. Reproducibility and performance of virtual karyotyping with SNP microarrays for the detection of chromosomal imbalances in formalin-fixed paraffin embedded tissues. Diagnostic Molecular Pathology. 19(3):127-134; 2010.

Nabi, F, Chang, S-M, Pratt, C.M., Paranilam, J., Peterson, L.E., Frias, M.E., Mahmarian, J.J. Coronary Artery Calcium Scoring in the Emergency Department: Identifying which patients with chest pain can be safely discharged home. Annals of Emergency Medicine. 56(3):220-229; 2010.

Chiu, D., Peterson, L.E., Elkind, M.S.V., Rosand, J., L.M. Gerber, Silverstein, M.D.  Glycine Antagonist in Neuroprotection(GAIN) Americas Trial Investigators. Comparison of outcomes after intracerebral hemorrhage and ischemic stroke. Int. J. Stroke and Cerebrovascular Dis. 19(3):225-229; 2010.

Chang, S.M., Nabi, F., Xu, J., Peterson, L.E., Achari, A., Pratt, C.M., Mahmarian, J.J. The coronary artery calcium score and stress myocardial perfusion imaging provide independent and complementary prediction of cardiac risk. J. Am. Coll. Cardiol. 54(20):1872-1882; 2009.

Peterson, L.E., Chen, X-W. Machine learning in biomedicine and bioinformatics. Int. J. Data Mining and Bioinformatics. 3(4):363-4; 2009.

Peterson, L.E., Lisboa, P.J.G. Biopattern analysis using machine learning methods. Int. J. Knowledge Engineering and Soft Data Paradigms. 1(3):193-194; 2009.

Peterson, L.E., Coleman, M.A. Logistic ensembles of random spherical linear oracles for microarray classification. Int. J. Data Mining and Bioinformatics. 3(4):382-397; 2009.

Peterson, L.E., Larin, K.V. Image classification of artificial fingerprints using Gabor wavelet edge detection, self-organizing maps, and Hermite/Laguerre neural networks. Int. J. Knowledge Engineering and Soft Data Paradigms. 1(3):239-256; 2009.

Chylack L.T., Jr, Peterson L.E., Feiveson, A.H., Wear, M.L., Manuel, F.K., Tung, W.H., Hardy, D., Marak, L., Cucinotta, F.A. NASA Study of Cataract in Astronauts (NASCA). Report 1: Cross-sectional study of the relationship of exposure to space radiation and risk of lens opacity. Radiat. Res. 172(1):10-20; 2009.

Kurt, M., Shaikh, K.A., Peterson, L.E., Kurrelmeyer, K.M., Shah, G., Nagueh, S.F., Fromm, R., Quinones, M.A., Zoghbi, W.A. Impact of contrast echocardiography on evaluation of ventricular function and clinical management in a large prospective cohort. J. Am. Coll. Cardiol. 53(9):802-810; 2009.

Peterson, L.E., K-Nearest Neighbor. Scholarpedia. 4(2): 1883; 2009.

Shaikh, K.A., Chang, S.M., Peterson, L.E., Rosendahl-Garcia, K., Quinones, M.A., Nagueh, S.F., Kurrelmeyer, K., Zoghbi, W.A. Safety of contrast administration for endocardial enhancement during stress echocardiography compared with noncontrast stress. Am. J. Cardiol. 102(11):1444-1450; 2008.

Hagenkord, J.M., Parwani, A.V., Lyons-Weiler, M.A., Alvarez, K., Amato, R., Gatalica, Z., Gonzalez-Berjon, J.M., Peterson, L.E., Dhir, R., Monzon, F.A. Virtual karyotyping with SNP microarrays reduces uncertainty in the diagnosis of renal epithelial tumors. Diagnostic Pathology. 3(44):1-13; 2008

Caglayan,E., Stauber, B., Collins, A.R., Lyon, C.J., Yin, F., Liu, J., Rosenkranz, S., Erdmann, E., Peterson, L.E., Ross, R.S., Tangirala, R.K., Hsueh, W.A. Differential roles of cardiomyocyte and macrophage PPAR? in cardiac fibrosis. Diabetes. 57(9):2470-2479; 2008.

Peterson, L.E., Miller, R.L. Association Between Radioactive Fallout From 1951-62 US Nuclear tests at the Nevada Test Site and cancer mortality in Midwestern US populations. Russian Journal of Ecology. 39(7):495-509; 2008.

Peterson, L.E., Coleman, M.A. Machine learning-based receiver operating characteristic (ROC) curves for crisp and fuzzy classification of DNA microarrays in cancer research. Int. J. of Approximate Reasoning. 47:17-36; 2008.

Acevedo, V.D., Gangula, R.D, Freeman, K.W., Li, R., Zhang, Y., Wang, F., Ayala, G., Peterson, L.E., Ittmann, M., Spencer, D.M. Inducible FGFR-1 leads to irreversible prostate adenocarcinoma and an epithelial to mesenchymal transition. Cancer Cell. 12(6):559-571; 2007.

Parmigiani G., Chen S., Iversen E.S., Friebel T., Finkelstein D., Anton-Culver H., Ziogas A., Weber B.L., Eisen A., Malone K.E., Daling J.R., Hsu L., Ostrander E.A., Peterson L.E., Schildkraut J.M., Isaacs C., Peshkin BN., Corio C., Leondaridis L., Tomlinson G., Amos C.I., Strong L.C., Berry D.A., Weitzel J.N., Sand S., Dutson D., Kerber R., Euhus D.M. Validity of models for prediction of BRCA1 and BRCA2 mutations. Annals of Internal Medicine. 147:441-450; 2007.

Pivovarov, S., Rukhin, A., Seredavina, T., Sushkova, N., Hill, P., Peterson, L.E.  Exposure subpopulations and peculiarities of individual dose distributions among inhabitants of the Semipalatinsk region.  Radiation Measurements. 42(6-7): 1033-1036; 2007.

Wu, H., Ghosh, S., Perrard, X.D., Feng, L., Garcia, G.E., Perrard, J.L., Sweeney, J.F., Peterson, L.E., Chan, L., Smith, W., Ballantyne, C.M. T-cell accumulation and RANTES up-regulation in adipose tissue in obesity. Circulation. 115(8):1029-38; 2007. 

Peterson, L.E., Ifeachor, E.C. Welcome to Source Code for Biology and Medicine. Source Code for Biology and Medicine. 1(1); 2006.

Chen, S., Iverson, E.S., Friebel, T., Finkelstein, D., Weber, B.L., Eisen, A., Peterson, L.E., Schildkraut, J.M., Isaacs, C., Peshkin, B.N., Corio, C., Leondaridis, L., Tomlinson, G., Dutson, D., Kerber, R., Amos, C.I., Strong, L.C., Berry, D.A., Euhus, D.M., Parmigiani, G. Characterization of BRCA1 and BRCA2 Mutations in a Large US Sample. J. Clin. Oncology. 24(6):863-71; 2006.

Lalani, S.R., Safiullah, A.A., Fernbach, S.D., Harutyunyan, K.G., Thaller, C., Peterson, L.E., McPherson, J.D., Gibbs, R.A., White, L.D., Hefner, M., Davenport, S.L.H., Graham Jr., J.M., Bacino, C.A., Glass, N.L., Towbin, J.A., Craigen, W.J., Neish, S.R., Lin, A.E., Belmont, J.W. Spectrum of CHD7 mutations in 110 individuals with CHARGE syndrome and genotype-phenotype correlation. Am. J. Hum. Genet. 78(2):303-314; 2006.

Peterson, L.E., Coleman, M.A. Comparison of gene identification based on artificial neural network pre-processing with k-means cluster and principal component analysis. Lecture Notes in Artificial Intelligence. 3849:267-276; 2006.

Coleman, M.A., Yin, E., Peterson, L.E., Nelson, D., Sorensen, K., Tucker, J.D., Wyrobek, A.J. Low-dose irradiation alters the transcript profiles of human lymphoblastoid cells including genes associated with cytogenetic radioadaptive response. Radiat. Res. 164(4):369-382; 2005.

Mao, J-H, Li, J., Jiang, T., Wu, D., Perez-Losada, J., Delrosario, R., Peterson, L.E., Balmain, A., Cai, W-W. Genomic signatures for radiation-induced mouse lymphoma. Oncogene. 24(53):7924-7934; 2005.

Al-Lamki, Z., Wali, Y.A., Wasifuddin, S.M., Zachariah, M., Al-Mjeni, R., Li, C., Muralitharan, S., Al-Kharusi, K., Gunaratne, P., Peterson, L.E., Gibbs, R., Gingras, M.C., Margolin, J.F. Identification of prognosis markers in pediatric high-risk acute lymphoblastic leukemia. Pediatr. Hematol. Oncol. 22(7), 629-643; 2005.

Friedman, L.C., Brown, A.E., Romero, C., Dulay, M.F., Peterson, L.E., Wehrman, P., Whisnand, D.J., Laufman, L., Lomax, J. Depressed mood and social support as predictors of quality of life in women receiving home health care. Quality of Life Research. 14(8):1925-1929; 2005.

McClain, K.L., Cai, Y-H., Hicks, J., Peterson, L.E., Yan, X-T., Che, S., Ginsberg, S. Expression profiling using human tissues in combination with RNA amplification and microarray analysis: assessment of Langerhans cell histiocytosis. Amino Acids. 28(3):279-290; 2005.

Ng, B., Yang, F., Huston, D.P., Yan, Y., Yang, Y., Xiong, Z., Peterson, L.E., Wang, H., Yang, X-F. Increased non-canonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes. J. Allergy Clin. Immunol. 114(6):1463-1470; 2004.

Li, J., Tao, J., Mao, J-H, Balmain, A., Peterson, L.E., Rao, P.H., Havlak, P., Gibbs, R., Cai, W-W. Genomic segmental polymorphisms in inbred mouse strains detected using whole genome BAC arrays. Nature Genetics. 36:952-954; 2004.

Cucinotta, F.A., Schimmerling, W., Wilson, J.W., Peterson, L.E., Saganti, P.B., Dicello, J.F. Uncertainties in estimates of the risks of late effects from space radiation. Advances in Space Research. 34(6):1383-1389; 2004.

Polnaszek, N., Kwabi-Addo, B., Peterson, L.E., Ozen, M., Greenberg, N., Ortega, S., Basilico, C. and Ittmann, M. FGF2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Research. 63:5754-5760; 2003.

Qiu, J., Gunaratne, P., Peterson, L.E., Khurana, D., Walsham, N., Loulseged, H., Karni, R.J., Roussel E., Gibbs, R.A., Margolin, J.F., Gingras, M.C. Novel potential ALL low-risk markers revealed by gene expression profiling with new high throughput SSH-CCS-PCR. Leukemia. 17:1891-1900; 2003.

Yin, E., Nelson, D. O., Coleman, M. A., Peterson, L. E., and Wyrobek, A. J. Gene expression changes in mouse brain after exposure to low-dose ionizing radiation. Int. J. Radiat. Biol. 79(10):759-775; 2003.

Hwang, I-R, Hsu, P.I., Peterson, L.E., Gutierrez, O., Kim, J.G., Graham, D.Y., Yamaoka, Y. Interleukin-6 genetic polymorphisms are not related to Helicobacter pylori-associated gastroduodenal diseases. Helicobacter. 8(2):142-148; 2003.

Peterson, L.E. Partitioning large-sample microarray-based gene expression profiles using principal components analysis. Computer Methods and Programs in Biomedicine. 70(2):107-119; 2003.

Hwang, I-R, Kodama, T., Kikuchi, S., Sakai, K., Peterson, L.E., Graham, D.Y., Yamaoka, Y. Effect of interleukin-1 polymorphisms on gastric mucosal interleukin-1ß production in helicobacter pylori infection. Gastroenterology. 123(6):1793-1803; 2002.

Peterson, L.E. Factor analysis of cluster-specific gene expression levels from cDNA microarrays. Computer Methods and Programs in Biomedicine. 69(3):179-188; 2002.

Peterson, L.E. Software Report: CLUSFAVOR 5.0: hierarchical cluster and principal component analysis of microarray-based transcriptional profiles. Genome Biology. 3(7)software0002.1-0002.8; 2002.

Carlson, N., Lechago, J., Richter, J., Sampliner, R.E., Peterson, L.E., Santella, R.M., Goldblum, J.R., Falk, G.W., Ertan, A., Younes, M. Acid suppression therapy may not alter malignant progression in Barrett's metaplasia showing p53 protein accumulation. Am. J. Gastroenterology. 97(6):1340-1345; 2002.

Sepulveda, A.R., Peterson, L.E., Shelton, J., Gutierrez, O., Graham, D.Y.  Histological patterns of gastritis in H. pylori infected individuals with family history of gastric cancer. Am. J. Gastroenterology. 97(6):1365-1370; 2002.

Sepulveda, A.R., Tao, H., Carloni, E., Sepulveda, J., Graham, D.Y., Otten, K., Gasbarrini, A., Peterson, L.E. Screening of gene expression profiles in gastric epithelial cells induced by Helicobacter pylori using microarray analysis. Alimentary Pharmacology and Therapeutics. 16(Suppl 2):145-157; 2002.

Ponomarev, A.L., Cucinotta, F.A., Sachs, R.K., Brenner, D.J. and Peterson, L.E. Extrapolation of the DNA fragment-size distribution after high-dose irradiation to predict effects at low doses. Radiat. Res. 156:594-597; 2001.

Cucinotta, F.A., Schimmerling, W., Wilson, J. W., Peterson, L.E., Badhwar, G.D., Saganti, P. B. and Dicello, J. F. Space radiation cancer risks and uncertainties for Mars missions. Radiat. Res. 156:682-688; 2001.

Carlsen,T.M, Peterson, L.E., Ulsh, B.A., Werner, C.A., Purvis, K.L., Sharber, A.C. Radionuclide Contamination at Kazakhstan's Semipalatinsk Test Site: Implications on human and ecological health. Human and Ecological Risk Assessment. 7(4):943-955; 2001.

Medina, D., Peterson, L.E., Moraes, R., Gay, J. Short-term exposure to estrogen and progesterone induces partial protection against N-nitroso-N-methylurea-induced mammary tumorigenesis in Wistar¯Furth rats. Cancer Letters. 169(1):1-6; 2001.

Friedman, L.C., Everett, T.E., Peterson, L.E., Ogbonnaya, K.I., Mendizabal, V. Compliance with Self-administered fecal occult blood test screening among low-income medical outpatients participating in a videotaped educational intervention. Journal of Cancer Education. 16:85-88; 2001.

Peterson, L.E., Bondar, A.Y., Volguina, I.V., Drozdova, V.D., Noschenko, A.D., Dreyer, Z.E., Weinberg, A.D. Case-control study of leukemia and environmental radiation fallout from the Chernobyl accident: Selection of hospital cases and multistage area probability sampling (MAPS) of controls in urban and rural areas of Ukraine. Cancer Research Therapy and Control. 11(2):113-124; 2001.

Plon, S.E., Peterson, L.E., Richards, C.S., Friedman, L.C. Mammography behavior after receiving a negative BRCA1 mutation test result in the Ashkenazim: A community-based study. Genetics in Medicine. 2(6):307-311; 2000.

Hayes, T.G., Peterson, L.E., Volguina, I.V., Rozin S., Tesch, P., Abeev, G., Weinberg, A.D. Establishment of a cancer registry in Semipalatinsk, Kazakhstan. Journal of Registry Management. 27(1):15-19; 2000.

Peterson, L.E., Cucinotta, F.A. Monte Carlo mixture model of lifetime cancer incidence risks for radiation on Shuttle and International Space Station. Mutation Research. 430(2):327-334; 1999.

Peterson, L.E., Barnholtz, J.S., Page, G.P., King, T.M., de Andrade, M., Amos, C.I. A Genome-wide search for susceptibility genes linked to alcohol dependence. Genetic Epidemiology. 17(S1):S295-300; 1999.

Page, G.P., King, T.M., Barnholtz, J.S., De Andrade, M., Peterson, L.E., Amos, C.I. Genome scans for genetic predisposition to alcoholism by use of TDT analysis. Genetic Epidemiology. 17(S1):S277-81; 1999.

Barnholtz, J.S., de Andrade, M., Page, G.P., Peterson, L.E., King, T.M., Amos, C.I. Assessing linkage of quantatative traits in a genome-wide scan of 285 markers on 22 chromosomes using a univariate variance components approach. Genetic Epidemiology. 17(S1):S49-54; 1999.

Peterson, L.E., Zhumadilov, Z.Z., Kripalani,S., Prouglo,Y.V., Wheeler, T.M., Gusev, B.I., Arem, R., Yonov, S., Weinberg, A.D. Diagnosis of benign and malignant thyroid disease in the East Kazakhstan Region of Kazakhstan: A case review of pathological findings of 2525 patients. Cancer Research Therapy and Control. 5(4):307-312; 1998.

Hayes, T.G., Peterson, L.E., Weinberg, A.D Implementation of guidelines for the diagnosis and treatment of breast cancer. Disease Management and Health Outcomes. 3(5):239-250; 1998.

Peterson, L.E. COVAR: Computer program for multifactor relative risks and tests of hypothesis using a variance-covariance matrix from linear and log-linear regression. Journal of Statistical Software. 2(4):i04; 1997.

Peterson, L.E. PIRLS: Poisson iteratively reweighted least squares computer program for additive, multiplicative, power, and non-linear models. Journal of Statistical Software. 2(5):io5; 1997.

Peterson, L.E., Dreyer, Z., Plon, S.E., Smith, J.L., Weinberg, A.D., McCarthy, P.M. Design and analysis of epidemiological studies of excess cancer among children exposed to Chernobyl radionuclides. Stem Cells. 15(S2):211-230; 1997.

Atwell, W., Hardy, A.C., Peterson, L.E. Organ radiation doses and lifetime risk of excess cancer for several space shuttle missions. Advances in Space Research. 12:139-148; 1996.

Peterson, L.E., Pepper, L.J., Hamm, P.B., Gilbert, S.L. Longitudinal Study of Astronaut Health: mortality in the years 1959-91. Radiat. Res. 133:257-264; 1993.

Cascade, P.A., Peterson, L.E., Wajszczuk, W.J., Mantel, J. Radiation exposure to patients undergoing percutaneous transluminal coronary angioplasty. American Journal of Cardiology. 59:996-997; 1987.


Monographs

Bartoletti, M., Barla, A., Bracciali, A., Klau, G., Peterson, L.E., Policriti, A., Tagliaferri, R.   (Eds).  Computational Intelligence Methods for Bioinformatics and Biostatistics, 2017, Lecture Notes in Computer Science (Lecture Notes in Bioinformatics), Vol. 10834, Berlin, Springer, 2019.

Peterson, L.E., Masulli, F., Russo, G. (Eds.) Computational Intelligence Methods for Bioinformatics and Biostatistics, 2013, Lecture Notes in Computer Science (Lecture Notes in Bioinformatics), Vol. 7845. Berlin, Springer, 2013.

Masulli, F., Peterson, L.E., Tagliaferri, R. (Eds.) Computational Intelligence Methods for Bioinformatics and Biostatistics II, 1st Edition, 2010, Vol. XIII, Softcover, Lecture Notes in Computer Science (Lecture Notes in Bioinformatics, Vol. 6160), 320 pages, ISBN-978-3-642-145. Berlin, Springer, 2010.


Book Chapters

Cucinotta, F.A., Peterson, L.E.  Progress in Predicting and Mitigating Health Risks of Space Radiation.   In: Space Physiology and Medicine, 4th Edition, (Eds. Nicogossian, A.), Springer, 2005.  

Pivovarov, S., Ruhkin, A., Seredavina, T., Peterson, L.E., Gorelkinskii, Y., Temirbaev, M. Experimental study of electron paramagnetic resonance (EPR) in Q-band capabilities for tooth enamel dosimetry on intact dens. In: Env. Prot. Against Radioactive Pollution. Pages 185-188 (Eds. Birsen, N., Kadyrzhanov, K.K.). Dordrecht-Netherlands, Kluwer Academic Publishers, 2003.

Plon, S.E., Peterson, L.E. Childhood Cancer, Heredity, and the Environment, Chapter 2. In: Principles and Practice of Pediatric Oncology. Pages 11-36 (Eds. Pizzo, P.A., Poplack, D.G.) Philadelphia, Lipincott-Raven, 1997.


Conference Proceedings

Ferrone, K.L, Kry, S.F., Ma, J., Peterson, L.E., Guan, F., Willis, C.E.  Technology Development of Magnetic Space Radiation Shielding in the Context of the Space Policy Environment. IEEE Aerospace Conference, 2019.

Peterson, L.E., Thompson, T.C.  In Silico ADME and Toxicity Prediction Using N-grams for Chemical Fingerprinting.  Proceedings of the 15th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB18).

Peterson, L.E., Kovyrshina, T. Permutation Test for Inferring Order of Somatic Mutations in Cancer Based on Binary Data.  International Conference on Intelligent Biology and Medicine (ICIBM16).

Peterson, L.E., Kovyrshina, T.  Statistical Randomization Test for Inferring Order of Somatic Mutations in Cancer.   Proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB16). 

Peterson, L.E.  Evolutionary algorithms applied to likelihood function maximization during Poisson, logistic, and Cox proportional hazards regression analysis. Proceedings of the 2014 IEEE Congress on Evolutionary Computation. Piscataway(NJ), IEEE Press, 2014.

Peterson, L.E., Paranilam, J., Xu, J., Monzon, F.A. Genome-wide germline single nucleotide polymorphisms for cancer classification in the Framingham heart study. Proceedings of the IEEE 2010 International Joint Conference on Neural Networks (IJCNN'10).  Piscataway(NJ), IEEE Press, 2010.

Ather, S., Peterson, L.E., Divakaran, V., Deswal, A., Bozkurt, B., Mann, D.L. Unsupervised cluster analysis and mortality risk in the digitalis investigation group (dig) trial of heart failure. Proceedings of the International Joint Conference on Neural Networks (IJCNN'09). Piscataway(NJ), IEEE Press, 2009.

Peterson, L.E., Ather, S., Divakaran, V., Deswal, A., Bozkurt, B., Mann, D.L. Improved propensity matching for heart failure using neural gas and self-organizing maps. Proceedings of the International Joint Conference on Neural Networks (IJCNN'09). Piscataway(NJ), IEEE Press, 2009.

Peterson, L.E.  Maximum likelihood logistic regression using metaheuristics. Proceedings of the IEEE 2009 International Conference on Machine Learning and Applications (ICMLA09).  Piscataway(NJ), IEEE Press, 2009.

Peterson, L.E., Larin, K.V. Hermite/Laguerre Neural Networks for Classification of Artificial Fingerprints From Optical Coherence Tomography.   Proceddings of the IEEE 2008 International Conference on Machine Learning and Applications (ICMLA08). Piscataway(NJ), IEEE Press, 2008.

Peterson, L.E., Coleman, M.A.  Text-mining protein-protein interaction corpus using concept clustering to identify intermittency.  Proceedings of the 2008 International Joint Conference on Neural Networks (IJCNN'08) of the 2008 IEEE World Congress on Computational Intelligence (WCCI'08), ISBN: 978-1-4244-1821-3.   Piscataway(NJ), IEEE Press, 2008.

Peterson, L.E. , Coleman, M.A.  Logistic ensembles for random spherical linear oracles.  2007 International Workshop on Machine Learning in Biomedicine and Bioinformatics (MLBB07); Proceedings of the 2007 IEEE International Conference of Machine Learning and Applications (ICMLA07).  Piscataway(NJ), IEEE Press, 2007.

Peterson, L.E.  Principal direction linear oracle for gene expression ensemble classification.  Proceedings of the 2007 IEEE International Joint Conference on Neural Networks (IJCNN07).  Piscataway(NJ), IEEE Press, 2007.

Peterson, L.E., Hoogeveen, R.C., Pownall, H.J., Morrisett, J.D. Classification analysis of surface-enhanced laser desorption/ionization mass spectral serum profiles for prostate cancer. Proceedings of the 2006 IEEE World Congress on Computational Intelligence (WCCI'06), ISBN:0-7803-9489-5.  Piscataway(NJ), IEEE Press, 2006.

Peterson, L.E., Ozen, M., Erdem, H., Amini, A., Gomez, L., Nelson, C.C., Ittmann, M.  Artificial neural network analysis of DNA microarray-based prostate cancer recurrence.   In: Proceedings of the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology(CIBCB'05), ISBN: 0-7803-9388-0.  Piscataway(NJ), IEEE Press, 2005.


US Gov't Reports

Cucinotta, F.A., Manuel, F.K., Iszard, G., Feiveson, A., Peterson, L.E., Hardy, D., Marak, L., Tung, W., Wear, M., Chylack, L.T., Jr.  Historical Study of Radiation Exposures and the Incidence of Cataracts in Astronauts.  NASA Center: Johnson Space Center, Publication Year: 2004, Added to NTRS: 2006-08-03, Document ID: 20060022181.

Ponomarev, A.L., Cucinotta, F.A., Sachs, R.K., Brenner, D.J., Peterson, L.E. Extrapolation of the DNA fragment-size distribution after high-dose irradiation to predict effects at low doses, NASA Center: Johnson Space Center, Publication Year: 2001, Added to NTRS: 2006-08-02, Document ID: 20040088724.

Cucinotta, F.A., Schimmerling, W., Wilson, J.W., Peterson, L.E., Saganti, P.B., Dicello, J.F.  Uncertainties in estimates of the risks of late effects from space radiation, NASA Center: Johnson Space Center, Publication Year: 2004, Added to NTRS: 2005-08-25, Document ID: 20050193731.

Peterson, L.E., Cucinotta, F.A., Wier, M.A. Epidemiologic Investigation of Radiation-Induced Cancer in the Longitudinal Study of Astronaut Health (LSAH). Confidential Technical Memorandum to Director, Space and Life Sciences Directorate, April, 2001. Houston, NASA-JSC, 2001.

Cucinotta, F.A., Schimmerling, W., Wilson, J.W., Peterson, L.E., Badhwar, G.D., Saganti, P.B., Dicello, J.F.  Space radiation cancer risks and uncertainties for Mars missions, NASA Center: Johnson Space Center, Publication Year: 2001, Added to NTRS: 2006-08-02, Document ID: 20040088717.

Peterson, L.E., Cucinotta, F.A.  Monte Carlo mixture model of lifetime cancer incidence risk from radiation exposure on shuttle and international space station, NASA Center: NASA (non Center Specific), Publication Year: 1999, Added to NTRS: 2006-08-02, Document ID: 20040141709.

Cucinotta, F.A., Schimmerling, W., Wilson, J.W., Peterson, L.E., Badhwar, G.D., Saganti, P.B., Dicello, J.F. Space Radiation Cancer Risk Projections for Exploration Missions: Uncertainty Reduction and Mitigation. NASA-JSC Document (JSC-29295). Houston, NASA-JSC, 2001.

Peterson, L.E., Schull, W.J., Davis, B.R., Buffler, P.A. Information bias and lifetime mortality risks of radiation-induced cancer. U.S. Nuclear Regulatory Commission, NUREG GR-0011 (April 1994). Office of Regulatory Research, U.S. Nuclear Regulatory Commission. Washington, D.C., NRC, 1994.

Peterson, L.E. Mortality Among Astronauts: General Patterns. Proceedings of the 1991 Annual Meeting of the NASA Occupational Health Program, New Orleans, LA. NASA Occupational Health Office, Washington, D.C., NASA, 1991.

Peterson, L.E., Nachtwey, D.S. Radiological Health Risks to Astronauts from Space Activities and Medical Procedures. NASA Technical Memorandum 102164. National Technical Information Service. Springfield(VA), NTIS, 1990.

Peterson, L.E., Rosenstein, M. Computer Program for Tissue Doses in Diagnostic Radiology (VAX and IBM PC Compatible Systems), April 1989. Center for Devices and Radiological Health, Food and Drug Administration, U.S. Department of Health and Human Services. Rockville (MD), FDA, 1989.


Working Papers

Peterson, L.E. Noise eigenspace projection for improving pattern classification accuracy and parsimony.   (In development).

Peterson, L.E.  Block-Boosted Regularization of Linear, Logistic, Poisson, and Cox PH Regression Using Correlation-Based Penalization.  SSRN eJournal, 2023.  https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4419320

Peterson, L.E. Skewness and Kurtosis of 18 Simulated Probability Distributions with Varying Sample Size and Scale.  SSRN eJournal, 2022. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4277814

Peterson, L.E.  Statistical randomization test for QCD intermittency in a single-event distribution.   arXiv:physics/0404016, 2004.    https://arxiv.org/abs/physics/0404016

Peterson, L.E., Lau, K.  Observation of Intermittency in Gene Expression on cDNA Microarrays    DOI: http://dx.doi.org/10.1186/gb-2002-3-7-preprint0005 (May, 2002)